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An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency
The bone wasting induced by estrogen deficiency is, in part, a consequence of increased T cell production of the osteoclastogenic cytokine TNF-α. This phenomenon is due to an expansion of T cells, but the responsible mechanism is unknown. We now show that ovariectomy (ovx) disregulates T lymphopoies...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283799/ https://ncbi.nlm.nih.gov/pubmed/16267136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505168102 |
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