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An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency

The bone wasting induced by estrogen deficiency is, in part, a consequence of increased T cell production of the osteoclastogenic cytokine TNF-α. This phenomenon is due to an expansion of T cells, but the responsible mechanism is unknown. We now show that ovariectomy (ovx) disregulates T lymphopoies...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ryan, Michaela Robbie, Shepherd, Rebecca, Leavey, Jennifer K., Gao, Yuhao, Grassi, Francesco, Schnell, Frederick J., Qian, Wei-Ping, Kersh, Gilbert J., Weitzmann, M. Neale, Pacifici, Roberto
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283799/
https://ncbi.nlm.nih.gov/pubmed/16267136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505168102
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