Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the requirement for the GH receptor (GHR) in osteoblast function in bone, we used...

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Vydáno v:Bone Res
Hlavní autoři: Singhal, Vandana, Goh, Brian C., Bouxsein, Mary L., Faugere, Marie-Claude, DiGirolamo, Douglas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472095/
https://ncbi.nlm.nih.gov/pubmed/26273494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201301006
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