Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the requirement for the GH receptor (GHR) in osteoblast function in bone, we used...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bone Res
Main Authors: Singhal, Vandana, Goh, Brian C., Bouxsein, Mary L., Faugere, Marie-Claude, DiGirolamo, Douglas J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472095/
https://ncbi.nlm.nih.gov/pubmed/26273494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201301006
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