Androgens and estrogens in skeletal sexual dimorphism

Bone is an endocrine tissue expressing androgen and estrogen receptors as well as steroid metabolizing enzymes. The bioactivity of circulating sex steroids is modulated by sex hormone-binding globulin and local conversion in bone tissue, for example, from testosterone (T) to estradiol (E2) by aromat...

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Bibliografiske detaljer
Main Authors: Laurent, Michaël, Antonio, Leen, Sinnesael, Mieke, Dubois, Vanessa, Gielen, Evelien, Classens, Frank, Vanderschueren, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2014
Fag:
Invited Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955330/
https://ncbi.nlm.nih.gov/pubmed/24385015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.122356
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