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Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis

Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and estrogens. According to the free hormone hypothesis, SHBG modulates the bioactivity of sex steroids by limiting their diffusion into target tissues. Still, the in vivo physiological role of circulating SHBG re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Laurent, Michaël R., Hammond, Geoffrey L., Blokland, Marco, Jardí, Ferran, Antonio, Leen, Dubois, Vanessa, Khalil, Rougin, Sterk, Saskia S., Gielen, Evelien, Decallonne, Brigitte, Carmeliet, Geert, Kaufman, Jean-Marc, Fiers, Tom, Huhtaniemi, Ilpo T., Vanderschueren, Dirk, Claessens, Frank
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066276/
https://ncbi.nlm.nih.gov/pubmed/27748448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35539
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