Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks that coordinate the development of these two anatomically adjacent tissues. The activin signaling pathway is an attractive candidate to fulfill such a role. Here, we generat...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Goh, Brian C., Singhal, Vandana, Herrera, Angelica J., Tomlinson, Ryan E., Kim, Soohyun, Faugere, Marie-Claude, Germain-Lee, Emily L., Clemens, Thomas L., Lee, Se-Jin, DiGirolamo, Douglas J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566533/
https://ncbi.nlm.nih.gov/pubmed/28659341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782128
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