Therapies for Musculoskeletal Disease: Can we Treat Two Birds with One Stone?

Por Girgis, Christian M., Mokbel, Nancy, DiGirolamo, Douglas J.
Publicado em 2014

Bone and Skeletal Muscle: Neighbors With Close Ties

Por DiGirolamo, Douglas J, Kiel, Douglas P, Esser, Karyn A
Publicado no J Bone Miner Res (2013)

Nrf2 is required for normal postnatal bone acquisition in mice

Por Kim, Jung-Hyun, Singhal, Vandana, Biswal, Shyam, Thimmulappa, Rajesh K, DiGirolamo, Douglas J
Publicado no Bone Res (2014)

Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

Por Singhal, Vandana, Goh, Brian C., Bouxsein, Mary L., Faugere, Marie-Claude, DiGirolamo, Douglas J.
Publicado no Bone Res (2013)

Administration of soluble activin receptor 2B increases bone and muscle mass in a mouse model of osteogenesis imperfecta

Por DiGirolamo, Douglas J., Singhal, Vandana, Chang, Xiaoli, Lee, Se-Jin, Germain-Lee, Emily L.
Publicado no Bone Res (2015)

Mode of growth hormone action in osteoblasts. VOLUME 282 (2007) PAGES 31666-31674

Por DiGirolamo, Douglas J., Mukherjee, Aditi, Fulzele, Keertik, Gan, Yujun, Cao, Xuemei, Frank, Stuart J., Clemens, Thomas L.
Publicado em 2009

Metastasis of hormone-independent breast cancer to lung and bone is decreased by α-difluoromethylornithine treatment

Por Richert, Monica M, Phadke, Pushkar A, Matters, Gail, DiGirolamo, Douglas J, Washington, Sharlene, Demers, Laurence M, Bond, Judith S, Manni, Andrea, Welch, Danny R
Publicado em 2005

Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism

Por Fan, Yong, Menon, Ram K., Cohen, Pinchas, Hwang, David, Clemens, Thomas, DiGirolamo, Douglas J., Kopchick, John J., Le Roith, Derek, Trucco, Massimo, Sperling, Mark A.
Publicado em 2009

Deletion of IGF-I Receptor (IGF-IR) in Primary Osteoblasts Reduces GH-Induced STAT5 Signaling

Por Gan, Yujun, Zhang, Yue, DiGirolamo, Douglas J., Jiang, Jing, Wang, Xiangdong, Cao, Xuemei, Zinn, Kurt R., Carbone, David P., Clemens, Thomas L., Frank, Stuart J.
Publicado em 2010

Tsc2 Is a Molecular Checkpoint Controlling Osteoblast Development and Glucose Homeostasis

Por Riddle, Ryan C., Frey, Julie L., Tomlinson, Ryan E., Ferron, Mathieu, Li, Yuanyuan, DiGirolamo, Douglas J., Faugere, Marie-Claude, Hussain, Mehboob A., Karsenty, Gerard, Clemens, Thomas L.
Publicado em 2014

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Por Goh, Brian C., Singhal, Vandana, Herrera, Angelica J., Tomlinson, Ryan E., Kim, Soohyun, Faugere, Marie-Claude, Germain-Lee, Emily L., Clemens, Thomas L., Lee, Se-Jin, DiGirolamo, Douglas J.
Publicado no J Biol Chem (2017)

Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice

Por Mavalli, Mahendra D., DiGirolamo, Douglas J., Fan, Yong, Riddle, Ryan C., Campbell, Kenneth S., van Groen, Thomas, Frank, Stuart J., Sperling, Mark A., Esser, Karyn A., Bamman, Marcas M., Clemens, Thomas L.
Publicado em 2010