Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass

Bone and skeletal muscle mass are highly correlated in mammals, suggesting the existence of common anabolic signaling networks that coordinate the development of these two anatomically adjacent tissues. The activin signaling pathway is an attractive candidate to fulfill such a role. Here, we generat...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Goh, Brian C., Singhal, Vandana, Herrera, Angelica J., Tomlinson, Ryan E., Kim, Soohyun, Faugere, Marie-Claude, Germain-Lee, Emily L., Clemens, Thomas L., Lee, Se-Jin, DiGirolamo, Douglas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566533/
https://ncbi.nlm.nih.gov/pubmed/28659341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.782128
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