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Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood

Abstract Accumulating evidence indicates a critical implication of DNA methylation in the brain development. We aim to determine whether the disruption of DNA methylation patterns in the developing brain adversely affects neurobehavioral phenotypes later in life in a sex-dependent manner. 5-Aza-2′-d...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Li, Yong, Ma, Qingyi, Dasgupta, Chiranjib, Halavi, Shina, Hartman, Richard E., Xiao, Daliao, Zhang, Lubo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161729/
https://ncbi.nlm.nih.gov/pubmed/27311770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9957-4
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