Inhibition of DNA Methylation in the Developing Rat Brain Disrupts Sexually Dimorphic Neurobehavioral Phenotypes in Adulthood

Abstract Accumulating evidence indicates a critical implication of DNA methylation in the brain development. We aim to determine whether the disruption of DNA methylation patterns in the developing brain adversely affects neurobehavioral phenotypes later in life in a sex-dependent manner. 5-Aza-2′-d...

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Veröffentlicht in:Mol Neurobiol
Hauptverfasser: Li, Yong, Ma, Qingyi, Dasgupta, Chiranjib, Halavi, Shina, Hartman, Richard E., Xiao, Daliao, Zhang, Lubo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161729/
https://ncbi.nlm.nih.gov/pubmed/27311770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-016-9957-4
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