Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the requirement for the GH receptor (GHR) in osteoblast function in bone, we used...

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Dettagli Bibliografici
Pubblicato in:Bone Res
Autori principali: Singhal, Vandana, Goh, Brian C., Bouxsein, Mary L., Faugere, Marie-Claude, DiGirolamo, Douglas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472095/
https://ncbi.nlm.nih.gov/pubmed/26273494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201301006
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