Osteoblast-restricted Disruption of the Growth Hormone Receptor in Mice Results in Sexually Dimorphic Skeletal Phenotypes

Growth hormone (GH) exerts profound anabolic actions during postnatal skeletal development, in part, through stimulating the production of insulin-like growth factor-1 (IGF-1) in liver and skeletal tissues. To examine the requirement for the GH receptor (GHR) in osteoblast function in bone, we used...

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Detalhes bibliográficos
Publicado no:Bone Res
Main Authors: Singhal, Vandana, Goh, Brian C., Bouxsein, Mary L., Faugere, Marie-Claude, DiGirolamo, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472095/
https://ncbi.nlm.nih.gov/pubmed/26273494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201301006
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