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Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

Mechanical forces transduced to cells through the extracellular matrix are critical regulators of tissue development, growth, and homeostasis, and can play important roles in directing stem cell differentiation. In addition to force-sensing mechanisms that reside at the cell surface, there is growin...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Driscoll, Tristan P., Cosgrove, Brian D., Heo, Su-Jin, Shurden, Zach E., Mauck, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472080/
https://ncbi.nlm.nih.gov/pubmed/26083918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.010
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