Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

Mechanical forces transduced to cells through the extracellular matrix are critical regulators of tissue development, growth, and homeostasis, and can play important roles in directing stem cell differentiation. In addition to force-sensing mechanisms that reside at the cell surface, there is growin...

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Опубликовано в: :Biophys J
Главные авторы: Driscoll, Tristan P., Cosgrove, Brian D., Heo, Su-Jin, Shurden, Zach E., Mauck, Robert L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2015
Предметы:
Cell Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472080/
https://ncbi.nlm.nih.gov/pubmed/26083918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.010
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