Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

Mechanical forces transduced to cells through the extracellular matrix are critical regulators of tissue development, growth, and homeostasis, and can play important roles in directing stem cell differentiation. In addition to force-sensing mechanisms that reside at the cell surface, there is growin...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Driscoll, Tristan P., Cosgrove, Brian D., Heo, Su-Jin, Shurden, Zach E., Mauck, Robert L.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Cell Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472080/
https://ncbi.nlm.nih.gov/pubmed/26083918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.05.010
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