Cargando...

Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:eLife
Autores principales: Heo, Su-Jin, Driscoll, Tristan P, Thorpe, Stephen D, Nerurkar, Nandan L, Baker, Brendon M, Yang, Michael T, Chen, Christopher S, Lee, David A, Mauck, Robert L
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148611/
https://ncbi.nlm.nih.gov/pubmed/27901466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18207
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!