Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity

Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovi...

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Sparad:
Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Heo, Su-Jin, Driscoll, Tristan P, Thorpe, Stephen D, Nerurkar, Nandan L, Baker, Brendon M, Yang, Michael T, Chen, Christopher S, Lee, David A, Mauck, Robert L
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2016
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5148611/
https://ncbi.nlm.nih.gov/pubmed/27901466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18207
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