Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients

The anti-estrogen tamoxifen is characterized by a large variability in response, partly due to pharmacokinetic differences. We examined circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients. Pharmacokinetic analysis was performed in mice, dosed at six different times (...

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Detaylı Bibliyografya
Yayımlandı:Breast Cancer Res Treat
Asıl Yazarlar: Binkhorst, Lisette, Kloth, Jacqueline S. L., de Wit, Annelieke S., de Bruijn, Peter, Lam, Mei H., Chaves, Ines, Burger, Herman, van Alphen, Robbert J., Hamberg, Paul, van Schaik, Ron H. N., Jager, Agnes, Koch, Birgit C. P., Wiemer, Erik A. C., van Gelder, Teun, van der Horst, Gijsbertus T. J., Mathijssen, Ron H. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2015
Konular:
Clinical Trial
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469299/
https://ncbi.nlm.nih.gov/pubmed/26050156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-015-3452-x
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