The Risk of QTc-Interval Prolongation in Breast Cancer Patients Treated with Tamoxifen in Combination with Serotonin Reuptake Inhibitors

PURPOSE: Antidepressants like the serotonin reuptake inhibitors (SRIs) are often used concomitantly with tamoxifen (e.g. for treatment of depression). This may lead to an additional prolongation of the QTc-interval, with an increased risk of cardiac side effects. Therefore we investigated whether th...

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Pubblicato in:Pharm Res
Autori principali: Hussaarts, Koen G. A. M., Berger, Florine A., Binkhorst, Lisette, Oomen - de Hoop, Esther, van Leeuwen, Roelof W. F., van Alphen, Robbert J., Mathijssen - van Stein, Daniëlle, de Groot, Natasja M. S., Mathijssen, Ron H. J., van Gelder, Teun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914733/
https://ncbi.nlm.nih.gov/pubmed/31845095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-019-2746-9
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