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The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides
When developing novel microbicide products for the prevention of HIV infection, the preclinical safety program must evaluate not only the active pharmaceutical ingredient but also the product itself. To that end, we applied several relatively standard toxicology study methodologies to female sheep,...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468677/ https://ncbi.nlm.nih.gov/pubmed/25845860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04954-14 |
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