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The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides
When developing novel microbicide products for the prevention of HIV infection, the preclinical safety program must evaluate not only the active pharmaceutical ingredient but also the product itself. To that end, we applied several relatively standard toxicology study methodologies to female sheep,...
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| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468677/ https://ncbi.nlm.nih.gov/pubmed/25845860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04954-14 |
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