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Preclinical Evaluation of the HIV-1 Fusion Inhibitor L'644 as a Potential Candidate Microbicide

Topical blockade of the gp41 fusogenic protein of HIV-1 is one possible strategy by which microbicides could prevent HIV transmission, working early against infection, by inhibiting viral entry into host cells. In this study, we examined the potential of gp41 fusion inhibitors (FIs) as candidate ant...

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Bibliographische Detailangaben
Hauptverfasser: Harman, Sarah, Herrera, Carolina, Armanasco, Naomi, Nuttall, Jeremy, Shattock, Robin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346626/
https://ncbi.nlm.nih.gov/pubmed/22330930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06108-11
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