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Mitochondrial ClpX activates a key enzyme for heme biosynthesis and erythropoiesis
The mitochondrion maintains and regulates its proteome with chaperones primarily inherited from its bacterial endosymbiont ancestor. Among these chaperones is the AAA+ unfoldase ClpX, an important regulator of prokaryotic physiology with poorly defined function in the eukaryotic mitochondrion. We ob...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467794/ https://ncbi.nlm.nih.gov/pubmed/25957689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.017 |
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