Functional Interactions between Erythroid Kruppel-like Factor (EKLF/KLF1) and Protein Phosphatase PPM1B/PP2Cβ

Por Yien, Yvette Y., Bieker, James J.
Publicado em 2012

EKLF/KLF1, a Tissue-Restricted Integrator of Transcriptional Control, Chromatin Remodeling, and Lineage Determination

Por Yien, Yvette Y., Bieker, James J.
Publicado em 2013

A role for iron deficiency in dopaminergic neurodegeneration

Por Yien, Yvette Y., Paw, Barry H.
Publicado no Proc Natl Acad Sci U S A (2016)

Mitochondrial transport of protoporphyrinogen IX in erythroid cells

Por Yien, Yvette Y., Ringel, Alessa R., Paw, Barry H.
Publicado no Oncotarget (2015)

Alternative splicing of Eklf/Klf1 in murine primary erythroid tissues

Por Yien, Yvette Y., Gnanapragasam, Merlin Nithya, Gupta, Ritama, Rivella, Stefano, Bieker, James J.
Publicado no Exp Hematol (2014)

Characterization of Genomic Deletion Efficiency Mediated by Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/Cas9 Nuclease System in Mammalian Cells

Por Canver, Matthew C., Bauer, Daniel E., Dass, Abhishek, Yien, Yvette Y., Chung, Jacky, Masuda, Takeshi, Maeda, Takahiro, Paw, Barry H., Orkin, Stuart H.
Publicado em 2014

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.

Por Canver, Matthew C., Bauer, Daniel E., Dass, Abhishek, Yien, Yvette Y., Chung, Jacky, Masuda, Takeshi, Maeda, Takahiro, Paw, Barry H., Orkin, Stuart H.
Publicado no J Biol Chem (2017)

Mitochondrial ClpX activates a key enzyme for heme biosynthesis and erythropoiesis

Por Kardon, Julia R., Yien, Yvette Y., Huston, Nicholas C., Branco, Diana S., Hildick-Smith, Gordon J., Rhee, Kyu Y., Paw, Barry H., Baker, Tania A.
Publicado no Cell (2015)

Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria

Por Yien, Yvette Y., Ducamp, Sarah, van der Vorm, Lisa N., Kardon, Julia R., Manceau, Hana, Kannengiesser, Caroline, Bergonia, Hector A., Kafina, Martin D., Karim, Zoubida, Gouya, Laurent, Baker, Tania A., Puy, Hervé, Phillips, John D., Nicolas, Gaël, Paw, Barry H.
Publicado no Proc Natl Acad Sci U S A (2017)

Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes

Por Seguin, Alexandra, Takahashi-Makise, Naoko, Yien, Yvette Y., Huston, Nicholas C., Whitman, Jared C., Musso, Gabriel, Wallace, Jared A., Bradley, Thomas, Bergonia, Hector A., Kafina, Martin D., Matsumoto, Mitsuyo, Igarashi, Kazuhiko, Phillips, John D., Paw, Barry H., Kaplan, Jerry, Ward, Diane M.
Publicado no J Biol Chem (2017)

The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability

Por Chung, Jacky, Bauer, Daniel E., Ghamari, Alireza, Nizzi, Christopher P., Deck, Kathryn M., Kingsley, Paul D., Yien, Yvette Y., Huston, Nicholas C., Chen, Caiyong, Schultz, Iman J., Dalton, Arthur J., Wittig, Johannes G., Palis, James, Orkin, Stuart H., Lodish, Harvey F., Eisenstein, Richard S., Cantor, Alan B., Paw, Barry H.
Publicado no Sci Signal (2015)

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

Por Grillo, Anthony S., SantaMaria, Anna M., Kafina, Martin D., Cioffi, Alexander G., Huston, Nicholas C., Han, Murui, Seo, Young Ah, Yien, Yvette Y., Nardone, Christopher, Menon, Archita V., Fan, James, Svoboda, Dillon C., Anderson, Jacob B., Hong, John D., Nicolau, Bruno G., Subedi, Kiran, Gewirth, Andrew A., Wessling-Resnick, Marianne, Kim, Jonghan, Paw, Barry H., Burke, Martin D.
Publicado no Science (2017)

Snx3 regulates recycling of the transferrin receptor and iron assimilation

Por Chen, Caiyong, Garcia-Santos, Daniel, Ishikawa, Yuichi, Seguin, Alexandra, Li, Liangtao, Fegan, Katherine H., Hildick-Smith, Gordon J., Shah, Dhvanit I., Cooney, Jeffrey D., Chen, Wen, King, Matthew J., Yien, Yvette Y., Schultz, Iman J., Anderson, Heidi, Dalton, Arthur J., Freedman, Matthew L., Kingsley, Paul D., Palis, James, Hattangadi, Shilpa M., Lodish, Harvey F., Ward, Diane M., Kaplan, Jerry, Maeda, Takahiro, Ponka, Prem, Paw, Barry H.
Publicado em 2013

Macrocytic Anemia and Mitochondriopathy Resulting from a Defect in Sideroflexin 4

Por Hildick-Smith, Gordon J., Cooney, Jeffrey D., Garone, Caterina, Kremer, Laura S., Haack, Tobias B., Thon, Jonathan N., Miyata, Non, Lieber, Daniel S., Calvo, Sarah E., Akman, H. Orhan, Yien, Yvette Y., Huston, Nicholas C., Branco, Diana S., Shah, Dhvanit I., Freedman, Matthew L., Koehler, Carla M., Italiano, Joseph E., Merkenschlager, Andreas, Beblo, Skadi, Strom, Tim M., Meitinger, Thomas, Freisinger, Peter, Donati, M. Alice, Prokisch, Holger, Mootha, Vamsi K., DiMauro, Salvatore, Paw, Barry H.
Publicado em 2013

TMEM14C is required for erythroid mitochondrial heme metabolism

Por Yien, Yvette Y., Robledo, Raymond F., Schultz, Iman J., Takahashi-Makise, Naoko, Gwynn, Babette, Bauer, Daniel E., Dass, Abhishek, Yi, Gloria, Li, Liangtao, Hildick-Smith, Gordon J., Cooney, Jeffrey D., Pierce, Eric L., Mohler, Kyla, Dailey, Tamara A., Miyata, Non, Kingsley, Paul D., Garone, Caterina, Hattangadi, Shilpa M., Huang, Hui, Chen, Wen, Keenan, Ellen M., Shah, Dhvanit I., Schlaeger, Thorsten M., DiMauro, Salvatore, Orkin, Stuart H., Cantor, Alan B., Palis, James, Koehler, Carla M., Lodish, Harvey F., Kaplan, Jerry, Ward, Diane M., Dailey, Harry A., Phillips, John D., Peters, Luanne L., Paw, Barry H.
Publicado em 2014