Silencing of CCR2 in myocarditis

BACKGROUND: Myocarditis is characterized by inflammatory cell infiltration of the heart and subsequent deterioration of cardiac function. Monocytes are the most prominent population of accumulating leucocytes. We investigated whether in vivo administration of nanoparticle-encapsulated siRNA targetin...

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Dettagli Bibliografici
Pubblicato in:Eur Heart J
Autori principali: Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, Nahrendorf, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465633/
https://ncbi.nlm.nih.gov/pubmed/24950695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu225
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