Silencing of CCR2 in myocarditis

BACKGROUND: Myocarditis is characterized by inflammatory cell infiltration of the heart and subsequent deterioration of cardiac function. Monocytes are the most prominent population of accumulating leucocytes. We investigated whether in vivo administration of nanoparticle-encapsulated siRNA targetin...

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Udgivet i:Eur Heart J
Main Authors: Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, Nahrendorf, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465633/
https://ncbi.nlm.nih.gov/pubmed/24950695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu225
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