Silencing of CCR2 in myocarditis

BACKGROUND: Myocarditis is characterized by inflammatory cell infiltration of the heart and subsequent deterioration of cardiac function. Monocytes are the most prominent population of accumulating leucocytes. We investigated whether in vivo administration of nanoparticle-encapsulated siRNA targetin...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, Nahrendorf, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465633/
https://ncbi.nlm.nih.gov/pubmed/24950695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu225
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