Silencing of CCR2 in myocarditis

BACKGROUND: Myocarditis is characterized by inflammatory cell infiltration of the heart and subsequent deterioration of cardiac function. Monocytes are the most prominent population of accumulating leucocytes. We investigated whether in vivo administration of nanoparticle-encapsulated siRNA targetin...

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Detalles Bibliográficos
Publicado en:Eur Heart J
Autores principales: Leuschner, Florian, Courties, Gabriel, Dutta, Partha, Mortensen, Luke J., Gorbatov, Rostic, Sena, Brena, Novobrantseva, Tatiana I., Borodovsky, Anna, Fitzgerald, Kevin, Koteliansky, Victor, Iwamoto, Yoshiko, Bohlender, Marina, Meyer, Soeren, Lasitschka, Felix, Meder, Benjamin, Katus, Hugo A., Lin, Charles, Libby, Peter, Swirski, Filip K., Anderson, Daniel G., Weissleder, Ralph, Nahrendorf, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Basic Science
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465633/
https://ncbi.nlm.nih.gov/pubmed/24950695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu225
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