Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma

Multiple myeloma is a B-cell malignancy stratified in part by cytogenetic abnormalities, including the high-risk copy number aberrations (CNAs) of +1q21 and 17p(−). To investigate the relationship between 1q21 CNAs and DNA hypomethylation of the 1q12 pericentromeric heterochromatin, we treated in vi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Blood
Main Authors: Sawyer, Jeffrey R., Tian, Erming, Heuck, Christoph J., Johann, Donald J., Epstein, Joshua, Swanson, Charles M., Lukacs, Janet L., Binz, Regina Lichti, Johnson, Marian, Sammartino, Gael, Zangari, Maurizio, Davies, Faith E., van Rhee, Frits, Morgan, Gareth J., Barlogie, Bart
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2015
Teme:
Lymphoid Neoplasia
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463736/
https://ncbi.nlm.nih.gov/pubmed/25943786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-632075
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki