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Identification of telomere dysfunction in Friedreich ataxia
BACKGROUND: Friedreich ataxia (FRDA) is a progressive inherited neurodegenerative disorder caused by mutation of the FXN gene, resulting in decreased frataxin expression, mitochondrial dysfunction and oxidative stress. A recent study has identified shorter telomeres in FRDA patient leukocytes as a p...
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| Publicado no: | Mol Neurodegener |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4462004/ https://ncbi.nlm.nih.gov/pubmed/26059974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0019-6 |
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