A carregar...
MutLα Heterodimers Modify the Molecular Phenotype of Friedreich Ataxia
BACKGROUND: Friedreich ataxia (FRDA), the most common autosomal recessive ataxia disorder, is caused by a dynamic GAA repeat expansion mutation within intron 1 of FXN gene, resulting in down-regulation of frataxin expression. Studies of cell and mouse models have revealed a role for the mismatch rep...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074104/ https://ncbi.nlm.nih.gov/pubmed/24971578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100523 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|