mTORC2/Rictor Signaling Disrupts Dopamine-Dependent Behaviors via Defects in Striatal Dopamine Neurotransmission

Disrupted neuronal protein kinase B (Akt) signaling has been associated with dopamine (DA)-related neuropsychiatric disorders, including schizophrenia, a devastating mental illness. We hypothesize that proper DA neurotransmission is therefore dependent upon intact neuronal Akt function. Akt is activ...

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Publicado en:J Neurosci
Autores principales: Dadalko, Olga I., Siuta, Michael, Poe, Amanda, Erreger, Kevin, Matthies, Heinrich J.G., Niswender, Kevin, Galli, Aurelio
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461689/
https://ncbi.nlm.nih.gov/pubmed/26063917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0887-15.2015
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