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Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding
BACKGROUND: The prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address “food-abuse” disorders. We demonstrate a molecular link between impairment of a central kinase (Akt) involved in insulin signaling...
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| Huvudupphovsmän: | , , , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182178/ https://ncbi.nlm.nih.gov/pubmed/21969871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025169 |
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