Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

BACKGROUND: The prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address “food-abuse” disorders. We demonstrate a molecular link between impairment of a central kinase (Akt) involved in insulin signaling...

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Библиографические подробности
Главные авторы: Speed, Nicole, Saunders, Christine, Davis, Adeola R., Owens, W. Anthony, Matthies, Heinrich J. G., Saadat, Sanaz, Kennedy, Jack P., Vaughan, Roxanne A., Neve, Rachael L., Lindsley, Craig W., Russo, Scott J., Daws, Lynette C., Niswender1, Kevin D., Galli, Aurelio
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182178/
https://ncbi.nlm.nih.gov/pubmed/21969871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025169
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