Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT) ensures the phasic nature of the DA signal, which underlies the ability of DA to encode reward prediction error, thereby driving motivation, attention, and behavioral learning. Disruptions to the DA system are impli...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: DiCarlo, Gabriella E., Aguilar, Jenny I., Matthies, Heinrich J.G., Harrison, Fiona E., Bundschuh, Kyle E., West, Alyssa, Hashemi, Parastoo, Herborg, Freja, Rickhag, Mattias, Chen, Hao, Gether, Ulrik, Wallace, Mark T., Galli, Aurelio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668686/
https://ncbi.nlm.nih.gov/pubmed/31094705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127411
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