Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT) ensures the phasic nature of the DA signal, which underlies the ability of DA to encode reward prediction error, thereby driving motivation, attention, and behavioral learning. Disruptions to the DA system are impli...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: DiCarlo, Gabriella E., Aguilar, Jenny I., Matthies, Heinrich J.G., Harrison, Fiona E., Bundschuh, Kyle E., West, Alyssa, Hashemi, Parastoo, Herborg, Freja, Rickhag, Mattias, Chen, Hao, Gether, Ulrik, Wallace, Mark T., Galli, Aurelio
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668686/
https://ncbi.nlm.nih.gov/pubmed/31094705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127411
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