Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT) ensures the phasic nature of the DA signal, which underlies the ability of DA to encode reward prediction error, thereby driving motivation, attention, and behavioral learning. Disruptions to the DA system are impli...

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Vydáno v:J Clin Invest
Hlavní autoři: DiCarlo, Gabriella E., Aguilar, Jenny I., Matthies, Heinrich J.G., Harrison, Fiona E., Bundschuh, Kyle E., West, Alyssa, Hashemi, Parastoo, Herborg, Freja, Rickhag, Mattias, Chen, Hao, Gether, Ulrik, Wallace, Mark T., Galli, Aurelio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668686/
https://ncbi.nlm.nih.gov/pubmed/31094705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127411
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