Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

The precise regulation of synaptic dopamine (DA) content by the DA transporter (DAT) ensures the phasic nature of the DA signal, which underlies the ability of DA to encode reward prediction error, thereby driving motivation, attention, and behavioral learning. Disruptions to the DA system are impli...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: DiCarlo, Gabriella E., Aguilar, Jenny I., Matthies, Heinrich J.G., Harrison, Fiona E., Bundschuh, Kyle E., West, Alyssa, Hashemi, Parastoo, Herborg, Freja, Rickhag, Mattias, Chen, Hao, Gether, Ulrik, Wallace, Mark T., Galli, Aurelio
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668686/
https://ncbi.nlm.nih.gov/pubmed/31094705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI127411
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