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Rescue of Dopamine Transporter Function in Hypoinsulinemic Rats by a D(2) Receptor–ERK-Dependent Mechanism

The dopamine (DA) transporter (DAT) is a major target for abused drugs and a key regulator of extracellular DA. A rapidly growing literature implicates insulin as an important regulator of DAT function. We showed previously that amphetamine (AMPH)-evoked DA release is markedly impaired in rats deple...

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Bibliographic Details
Main Authors: Owens, W. Anthony, Williams, Jason M., Saunders, Christine, Avison, Malcolm J., Galli, Aurelio, Daws, Lynette C.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310897/
https://ncbi.nlm.nih.gov/pubmed/22357848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3759-11.2012
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