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Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

BACKGROUND: The prevalence of obesity has increased dramatically worldwide. The obesity epidemic begs for novel concepts and therapeutic targets that cohesively address “food-abuse” disorders. We demonstrate a molecular link between impairment of a central kinase (Akt) involved in insulin signaling...

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主要な著者: Speed, Nicole, Saunders, Christine, Davis, Adeola R., Owens, W. Anthony, Matthies, Heinrich J. G., Saadat, Sanaz, Kennedy, Jack P., Vaughan, Roxanne A., Neve, Rachael L., Lindsley, Craig W., Russo, Scott J., Daws, Lynette C., Niswender1, Kevin D., Galli, Aurelio
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182178/
https://ncbi.nlm.nih.gov/pubmed/21969871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025169
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