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Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis

Insulin signaling in the central nervous system (CNS) regulates energy balance and peripheral glucose homeostasis. Rictor is a key regulatory/structural subunit of the mTORC2 complex and is required for hydrophobic motif site phosphorylation of Akt at serine 473. To examine the contribution of neuro...

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Bibliografske podrobnosti
Main Authors: Kocalis, Heidi E., Hagan, Scott L., George, Leena, Turney, Maxine K., Siuta, Michael A., Laryea, Gloria N., Morris, Lindsey C., Muglia, Louis J., Printz, Richard L., Stanwood, Gregg D., Niswender, Kevin D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060224/
https://ncbi.nlm.nih.gov/pubmed/24944899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.01.014
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