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Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-induced hyperphagia

OBJECTIVE: Food intake is highly regulated by central homeostatic and hedonic mechanisms in response to peripheral and environmental cues. Neutral energy balance stems from proper integration of homeostatic signals with those “sensing” the rewarding properties of food. Impairments in brain insulin s...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Dadalko, Olga I., Niswender, Kevin, Galli, Aurelio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939830/
https://ncbi.nlm.nih.gov/pubmed/27441217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2015.e00025
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