Φορτώνει......

Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus

The acute neurotoxicity of oligomeric forms of amyloid-β 1-42 (Aβ) is implicated in the pathogenesis of Alzheimer’s disease (AD). However, how these oligomers might first impair neuronal function at the onset of pathology is poorly understood. Here we have examined the underlying toxic effects cause...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Whitcomb, Daniel J., Hogg, Ellen L., Regan, Philip, Piers, Thomas, Narayan, Priyanka, Whitehead, Garry, Winters, Bryony L., Kim, Dong-Hyun, Kim, Eunjoon, St George-Hyslop, Peter, Klenerman, David, Collingridge, Graham L., Jo, Jihoon, Cho, Kwangwook
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2015
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460729/
https://ncbi.nlm.nih.gov/pubmed/26055072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10934
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!