Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β

Amyloid-β (Aβ) plays an important role in Alzheimer's disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent endocytosis pathway, in which endophilin2 is one of...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Zhang, Jifeng, Yin, Yichen, Ji, Zhisheng, Cai, Zhenbin, Zhao, Bo, Li, Jiong, Tan, Minghui, Guo, Guoqing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516760/
https://ncbi.nlm.nih.gov/pubmed/28758034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/8197085
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