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Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β

Amyloid-β (Aβ) plays an important role in Alzheimer’s disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent endocytosis pathway, in which endophilin2 is one of the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Jifeng Zhang, Yichen Yin, Zhisheng Ji, Zhenbin Cai, Bo Zhao, Jiong Li, Minghui Tan, Guoqing Guo
פורמט: Artigo
שפה:Inglês
יצא לאור: Hindawi Limited 2017-01-01
סדרה:Neural Plasticity
גישה מקוונת:http://dx.doi.org/10.1155/2017/8197085
תגים: הוספת תג
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