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Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models
Increased levels of the mitochondria-shaping protein Opa1 improve respiratory chain efficiency and protect from tissue damage, suggesting that it could be an attractive target to counteract mitochondrial dysfunction. Here we show that Opa1 overexpression ameliorates two mouse models of defective mit...
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| Pubblicato in: | Cell Metab |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457891/ https://ncbi.nlm.nih.gov/pubmed/26039449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.04.016 |
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