Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors

The signal peptide peptidases (SPPs) are biomedically important proteases implicated as therapeutic targets for hepatitis C (human SPP, (hSPP)), plasmodium (Plasmodium SPP (pSPP)), and B-cell immunomodulation and neoplasia (signal peptide peptidase like 2a, (SPPL2a)). To date, no drug-like, selectiv...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Ran, Yong, Ladd, Gabriela Z., Ceballos-Diaz, Carolina, Jung, Joo In, Greenbaum, Doron, Felsenstein, Kevin M., Golde, Todd E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457840/
https://ncbi.nlm.nih.gov/pubmed/26046535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128619
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker