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Shifting a complex debate on γ-secretase cleavage and Alzheimer's disease

EMBO J 31 10, 2261–2274 (2012); published online 04132012 Chávez-Gutiérrez et al (2012) examine the effects of Alzheimer's disease (AD) causing presenilin (PSEN) and amyloid β precursor protein (APP) mutations on intramembrane cleavage catalyzed by γ-secretase. These data provide definitive ins...

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Bibliografische gegevens
Hoofdauteurs: Golde, Todd E, Ran, Yong, Felsenstein, Kevin M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364746/
https://ncbi.nlm.nih.gov/pubmed/22505028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.111
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