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γ-Secretase Inhibitors and Modulators
γ-Secretase is a fascinating, multi-subunit, intramembrane-cleaving protease that is now being considered as a therapeutic target for a number of diseases. Potent, orally bioavailable γ-secretase inhibitors (GSIs) have been developed and tested in humans with Alzheimer's disease (AD) and cancer...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857966/ https://ncbi.nlm.nih.gov/pubmed/23791707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.06.005 |
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