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γ-Secretase Inhibitors and Modulators

γ-Secretase is a fascinating, multi-subunit, intramembrane-cleaving protease that is now being considered as a therapeutic target for a number of diseases. Potent, orally bioavailable γ-secretase inhibitors (GSIs) have been developed and tested in humans with Alzheimer's disease (AD) and cancer...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Golde, Todd E., Koo, Edward H., Felsenstein, Kevin M., Osborne, Barbara A., Miele, Lucio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857966/
https://ncbi.nlm.nih.gov/pubmed/23791707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2013.06.005
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