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Shifting a complex debate on γ-secretase cleavage and Alzheimer's disease
EMBO J 31 10, 2261–2274 (2012); published online 04132012 Chávez-Gutiérrez et al (2012) examine the effects of Alzheimer's disease (AD) causing presenilin (PSEN) and amyloid β precursor protein (APP) mutations on intramembrane cleavage catalyzed by γ-secretase. These data provide definitive ins...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364746/ https://ncbi.nlm.nih.gov/pubmed/22505028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.111 |
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