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Identification of Human Epididymis Protein-4 as a Novel Fibroblast-Derived Mediator of Fibrosis

The functional contribution of myofibroblasts in fibrosis is not well understood(1–3). Using a novel genetic mouse model to track and isolate myofibroblasts, we performed gene expression profiling followed by biological validation to identify human epididymis protein 4 (HE4, also known as WAP 4-disu...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: LeBleu, Valerie S., Teng, Yingqi, O’Connell, Joyce T., Charytan, David, Müller, Gerhard A, Müller, Claudia A, Sugimoto, Hikaru, Kalluri, Raghu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457508/
https://ncbi.nlm.nih.gov/pubmed/23353556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2989
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