Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells

HOX genes are highly expressed in many acute myeloid leukemia (AML) samples, but the patterns of expression and associated regulatory mechanisms are not clearly understood. We analyzed RNA sequencing data from 179 primary AML samples and normal hematopoietic cells to understand the range of expressi...

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Publicat a:Leukemia
Autors principals: Spencer, David H., Young, Margaret A., Lamprecht, Tamara L., Helton, Nichole M., Fulton, Robert, O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Miller, Christopher A., Klco, Jeffery M., Wilson, Richard K., Ley, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456213/
https://ncbi.nlm.nih.gov/pubmed/25600023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.6
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