Genetic Heterogeneity of Induced Pluripotent Stem Cells: Results from 24 Clones Derived from a Single C57BL/6 Mouse

Induced pluripotent stem cells (iPSCs) have tremendous potential as a tool for disease modeling, drug testing, and other applications. Since the generation of iPSCs “captures” the genetic history of the individual cell that was reprogrammed, iPSC clones (even those derived from the same individual)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Cheng, Klco, Jeffery M., Helton, Nichole M., George, Daniel R., Mudd, Jacqueline L., Miller, Christopher A., Lu, Charles, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Wilson, Richard K., Ley, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370741/
https://ncbi.nlm.nih.gov/pubmed/25799070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120585
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